Esperance de Tunis will welcome Etoile du Sahel in the 2018 CAF Champions League quarter-final first-leg match at the Stade Olympique de Radès in Tunisia on Saturday.
Kick-off is at 21h00 CAT.
The Tunisian champions finished as runners-up in Group A behind Egyptian giants Al Ahly having collected 11 points from six games.
As a result, Esperance advanced to the continental club competition which will conclude in November 2018.
The Blood and Gold will look to their 25-year-old striker Haythem Jouini as they target a victory in the first-leg encounter.
Esperance have lifted the Champions League title twice and they are looking to secure their third trophy.
Meanwhile, Etoile dominated Group D which they won ahead of runners-up C.D Primeiro de Agosto of Angola having accumulated 12 points from six games.
The dominance in the group stage earned the Tunisian side a place in the quarter-finals.
Etoile's key player is 31-year-old forward Amine Chermiti, who will be keen to score and help his side overcome Esperance.
The Red and White are hoping to win their second Champions League title having clinched the 2007 tournament.
Ethiopian match referee Bamlak Tessema Weyesa will be in charge of the game between Esperance and Etoile.