Mouloudia Club d'Alger will take on Entente Sportive de Setif in the 2018 CAF Champions League Group B game at the Stade du 5-Juillet-1962 in Algeria on Tuesday.
Kick-off is at 15h00 CAT.
The Algerian side suffered a 2-0 defeat to Moroccan outfit Difaa El Jadidi away in their previous Group B game over a week ago.
They are placed fourth on the Group B table having collected five points from five games. They are behind second-placed El Jadida on the head-to-head rule.
Alger will reach the knockout stages if they beat Setif and El Jadidi lose to TP Mazembe.
They are undefeated at home in this year's Champions League having recorded two wins and two draws.
Meanwhile, Setif played to a 1-1 with Mazembe away in their previous Group B game over a week ago.
As a result, the Algerian side is placed third on the Group B table having collected five points from five matches. They are five points behind group leaders Mazembe.
They can only qualify for the quarter-finals if they defeat Alger and the other result goes their way.
Setif are winless in this year's Champions League having recorded two draws and two defeats.
Seychelles match referee Bernard Camille will officiate the game between Alger and Setif.
Alger overcame Setif 1-0 in a Group B game in Algeria last May.