Club Africain will face off with TP Mazembe in the 2018/19 CAF Champions League Group C game on Tuesday.
Kick-off is at 18h00 CAT.
The match will be played at the Stade Olympique de Radès in the Tunisian city of Radès.
Africain suffered an 8-0 defeat to TP Mazembe away in their second Group C match which was played over a week ago.
The Tunisian Ligue Professionnelle side remained third on the group standings - three points behind second-placed Mazembe.
Experienced forward Oussama Darragi is the dangerman for Africain and he will be eager to lead his side to victory against Mazembe.
Meanwhile, Mazembe will be targeting another victory over a wounded Africain side.
The DR Congolese Ligue 1 side is now placed second on the group standings - three points behind the leaders CS Constantine of Algeria.
Tresor Mputu, who netted twice against Africain, is a key for Mazembe and the forward will be keen to inspire his side to victory in Tunisia.
Botswana referee Joshua Bondo will officiate the game between Africain and Mazembe.