Paris Saint-Germain look set to be without another of their star players when they take on Manchester United in the first-leg of their UEFA Champions League Round of 16 tie on Tuesday evening.
The Uruguay international is a major doubt for the first-leg clash at Old Trafford after picking up a hip injury in the club's 1-0 win over Bordeaux this past weekend.
PSG are already without the services of star forward Neymar for the two-legged tie while midfielder Marco Verratti is yet to return to full fitness.
This will come as a major boost for the Red Devils who were clear underdogs when the knockout stage fixtures were confirmed late last year.
United, though, have turned things around since Jose Mourinho's sacking and are currently on an 11-game unbeaten run.
Cavani has scored 22 goals in 26 games across all competitions this season.